1474034-05-3 omaveloxolone

Pwopriyete

Aparans blan nan poud blan-blan
Pwen bouyi: 662. 0 ± 55. 0 degre
Dansite 1.19 ± 0. 1 g/cm3
Depo tanperati. Magazen nan -20 degre
solubility pi gran pase oswa egal a 55.5 mg/ml nan DMSO; solubl nan H2O; Pi gran pase oswa egal a 25.05 mg/ml nan EtOH
PKA13.71 ± 0. 70

 

Aplikasyon:

OMAVELOXOLONE (Non Komès: Skyclarys) se yon medikaman ki itilize pou trete ataksya Friedlich. Apwouve pa Administrasyon Manje ak Medikaman Etazini (FDA) sou 28 fevriye, 2023, vin premye dwòg tretman an espesyalman vize Friedrichshafen ataksya

 

Sinonim:

Omaveloxolone

1474034-05-3

Rta -408

RTA 408

Nrf 1- activator -1

Skyclarys

omaveloxolona

omaloksolonòm

RTA408

N-[(4as, 6ar, 6bs, 8ar, 12as, 14ar, 14bs) -11- cyano -2, 2,6a, 6b, 9,9,12a-heptamethyl -10, 14-} dioxo -1, 3,4,5,6,7,8,8a, 14a, 14b-decahydropicen -4 a-il] -2, 2- difluoropropanamide

Propanamid, n-(2- cyano -3, 12- dioxo -28- noroleana -1, 9 (11) -dien {{9}

N-(2- Cyano -3, 12- dioxo -28- noroleana -1, 9 (11) -dien -17- yl) -2, {{{{}}}} {{{} {{{{}}} {{{{}} {{{

N-(11- Cyano -2, 2,6a, 6b, 9,9,12a-heptmethyl -10, 14- dioxo -1, 3,4,5,6a, 6b, 7,8, 8, 8, 7,8, 8a, 9,10,12a, 14,14a, 14b-hexadecahydro -2 h-picen -4 a-il) -2-2- difluoropropionamide

N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-Cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3 , 4,5,6,6a, 6b, 7,8,8a, 9,10,12a, 14,14a, 14b-hexadecahydropicen -4 A (2h) -yl) -2, 2- difluoropropanamide

N-(2- Cyano -3, 12- dioxo -28- noroleana -1, 9 (11) -dien -17- yl) {{10} Omaveloxolone

 

Baj popilè: 1474034-05-3 OmaveLoxolone, Lachin {{1}