120685-11-2 Midostaurin

Pwopriyete

Aparans blan solid
Pwen k ap fonn: 235-260 degre
Dansite 1.47 ± 0. 1 g/cm3
Depo tanperati. Sele nan sèk, magazen nan frizè, anba -20 degre
Solubility soluble nan DMSO (15 mg/mL), MDC (10 mg/mL), methanol (5 mg/mL), 100% etanòl (2.5 mg/mL), ak DMF (20 mg/mL).
PKA14.19 ± 0. 70

 

Aplikasyon:

Midostaurin (non komès: Rydapt) se yon ti molekil oral molekil milti-sib tirozin kinaz inibitè prensipalman itilize nan trete kalite espesifik kansè nan. ‌

Midostaurin se sitou itilize nan trete pasyan granmoun ki fèk dyagnostike FLT3 mitasyon pozitif egi myeloid lesemi (AML). Anplis de sa, li se tou itilize nan trete pwogrese mastocytosis sistemik (ASM), mastocytosis sistemik ak asosye maladi ematolojik (SM-Ahn), oswa lesemi selil ma (MCL).

 

Sinonim:

Midostaurin

120685-11-2

4'-n-benzoylstaurosporine

PKC -412

Benzoylstaurosporine

CGP -41251

PKC 412

N-benzoylstaurosporine

midostaurina

midostaurine

NVP-PKC412

Chebi: 63452

Nsc -656576

N-((9s, 10r, 11r, 13r) -10- methoxy -9- methyl -1- oxo -2, 3,10,11,12, 13- hexahydro -9 { }} H, 9h-diindolo (1,2, 3- Gh: 3 ', 2', 1'-lm) pyrrolo (3, {{27}

4'-n-benzoyl staurosporine

Benzamid, N- (2,3,9,10,11, 12- hexahydro -9- methoxy -8- methyl -1- oxo -8, 12- epoksid {{{ 12}} H, 8h -2, 7b, 12a-triazadibenzo (a, g) cyclonona (CDE) trinden -10- yl) -n-methyl-, (8alpha, 9beta, 10beta, 12alpha)-

N-[(5s, 6r, 7r, 9r) -6- methoxy -5- methyl -14- oxo -6, 7 , 8,9,15, 16- hexahydro -5 h, 14h -5, 9- epoksid {{1 8}} b, 9a, 15- triazadibenzo [b, h] cyclonona [1,2,3, {{24}

 

Baj popilè: 120685-11-2 Midostaurin, Lachin 120685-11-2 Midostaurin Konpayi fabrikasyon, Swèd