361442-04-8 Saxagliptin

Pwopriyete

Aparans blan nan koupe-blan solid
Pwen k ap fonn: 103 - 107 degre
Pwen bouyi: 548.7 ± 35. 0 degre
Dansite 1.35
Flash Point: 548.7 degre
Depo tanperati. 2-8 degre
Solubility DMSO (yon ti kras), methanol (ti kras)
PKA15.12 ± 0. 40
Estabilite: tanperati sansib

 

Aplikasyon:

Shagliptin se yon kalite dwòg ipoglisemi ak yon inhibiteur konpetitif nan dipeptidyl peptidase 4 (DPP4), ki ka diminye pousantaj la inaktivasyon nan incretin ak ogmante konsantrasyon san li yo, konsa diminye jèn la ak konsantrasyon glikoz nan san nan kalite 2 dyabèt nan yon fason glikoz nan glikoz.
Depi efikasite nan pwodui sa a pou dyabèt tip 1 ak dyabèt ketoacidosis pa te detèmine, pwodui sa a pa itilize pou pasyan ki gen dyabèt tip 1 oswa dyabèt ketoacidosis.

 

Sinonim:

Saksagliptin

Onglyza

361442-04-8

Saxagliptin anidrid

Saksagliptine

(1s, 3s, 5s) -2- ((2s) -2- amino -2- (3- hydroxyadamantan {{8} } yl) acetyl) -2- azabicyclo [3.1. 0] hexane -3- carbonitrile

(1s, 3s, 5s) -2- ((2s) -amino (3- hydroxytricyclo (3.3.1.13,7) Dec {{1 2}} yl) acetyl) -2- azabicyclo (3.1. 0) hexane -3- carbonitrile

(1s, 3s, 5s) -2- [(2s) -2- amino -2- (3- hydroxy -1- Adamant yl) asetil] -2- azabicyclo [3.1. 0] hexane -3- carbonitrile

(1s, 3s, 5s) -2- [(2s) -2- amino -2- (3- hydroxyadamantan {{8} } yl) acetyl] -2- azabicyclo [3.1. 0] hexane -3- carbonitrile

1073057-20-1

Saksagliptin

(S) -3- hydroxyadamantylglycine-l-cis -4, 5- methanoprolinenitrile TFA sèl

(1s, 6s) -2- (2- Adamantan -1- yl -2- amino-acetyl) -2- aza-bicyclo [3.1.

(1s, 3s, 5s) -2- ((2s) -amino (3- hydroxytricyclo (3.3.1.1 (SUP 3,7)) Dec -1- yl) asetil) -2- azabicyclo (3.1. 0) hexane -3- carbonitrile

(1s, 3s, 5s) -2- [(2s) -2- amino -2- (3- hydroxyadamantan -1- yl) asetil] -2- azabicyclo [3.1. 0] hexane -3- carbonitrile; 2,2, 2- asid trifluoroacetic

 

 

 

Baj popilè: 361442-04-8 Saxagliptin, Lachin 361442-04-8 manifaktirè saxagliptin, founisè